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2009/02/26

Analysis of ongoing dynamics in neural networks

柳川透くんの論文のアブストラクトです。

Yanagawa, T. and Mogi, K. (2009) Analysis of ongoing dynamics in neural networks. Neuroscience Research, in press.

Abstract
Spontaneous neural activities in the cerebral cortex exhibit complex spatio-temporal patterns in the absence of sensory inputs (Arieli et al., 1995; Arieli et al., 1996), wandering among the intrinsic set of cortical states (Tsodyks et al., 1999; Kenet et al., 2003). Elucidating the nature of such spontaneous activities is one of the most intriguing challenges in the effort to understand the computational principles employed by the brain. The precise mechanism behind these salient phenomena, however, is not known. Here we model the ongoing dynamics of generic neural networks with attractor states using a conductance-based neuron model. Our realistic modeling shows the existence of up-states and down-states in the membrane potential, where the up-states exist as spatially clustered patches moving within the network. Our analysis shows that up-states are sustained by the balance between excitatory and inhibitory inputs. Synaptic depression and depolarization-dependent potassium channels can cause the transitions from the up-states to down-states by affecting the dynamics in differential manners. The velocity of patches depends on the firing frequency of excitatory neurons affected by contributing factors. These results suggest that the switching dynamics can be produced by the interactions within the local network, revealing the constraints on the nature of autonomous dynamics within the cortex.

2月 26, 2009 at 07:31 午前 |

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Dear;Mr.Mogi

Congratulations!!!!!

(I am very happy to know that you have a wonderful student.)

投稿: Yoshiko.T | 2009/02/26 22:39:01

eigo〰!

なのに、英語とは思えぬほど知らない単語ばっかりです!!!!
柳川さんと茂木さんはこんな世界を中心に生きているのですか!!!!
やっぱ すごいなぁ!!!!
茂木さん、私たちとつき合っていていいのですかぁ¿?¿?
なんて、ちょっと思います。
私たちは嬉しい限りです!(^^)!

まったくわかりませんが、訳されたからと言って
理解できる内容とは思いません(*ε*ι)❀❁✾
お二人とも素晴らしい❢❢❢❢❢
お疲れ様です(@▼@)✧✧✧

投稿: | 2009/02/26 20:39:15

 アブストラクトなっげー!!!!!!

 うぅぅ…これが東工大クオリティというものか…

 まだまだや…自分、まだまだや…

投稿: | 2009/02/26 10:48:17

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